Notification Text

Human Papillomavirus (HPV) DNA Genotyping

Regular Screening for Early Intervention
What is HPV?

Human Papillomavirus (HPV) is a very common virus that can infect both men and women. Most HPV infections go away on their own, but some types can persist and cause health problems such as genital warts, precancerous lesions, and even cervical cancer.

What is HPV DNA Genotyping?

HPV DNA Genotyping is a molecular test that detects and identifies specific HPV types. By knowing the exact type of HPV present, doctors can better assess the risk of developing serious conditions and recommend appropriate follow-up or treatment.

What does the test detect?

This test screens for 28 HPV types, divided into:

  • 19 High-Risk HPV types (linked to cervical cancer and precancerous changes):
    16, 18, 26, 31, 33, 35, 39, 45, 51, 52, 53, 56, 58, 59, 66, 68, 69, 73 and 82

  • 9 Low-Risk HPV types (commonly associated with genital warts or low-grade changes):
    6, 11, 40, 42, 43, 44, 54, 61 and 70

Why is this test important?
  • Detects if you are carrying high-risk or low-risk HPV types

  • Helps identify women at increased risk for cervical cancer

  • Supports clinical decisions on monitoring, treatment, or preventive measures

  • Complements cytology test and routine cervical screening

Why combine HPV Test with LBC?
  • Higher Sensitivity – Improves detection rate and reduces unnecessary colposcopy.
  • Early Detection – Identifies HPV infection even before abnormal cell changes appear.
  • Better Management – Enables closer monitoring and timely prevention.
Specimen Requirements
Clinical usageDetection and identification of 28 types of HPV as below:
• 19 high-risk HPV:
16, 18, 26, 31, 33, 35, 39, 45, 51, 52, 53, 56, 58, 59, 66, 68, 69, 73 & 82
• 9 low-risk HPV:
6, 11, 40, 42, 43, 44, 54, 61 & 70
Type of sample• Cervical Swab (LBC Preservative Solution with Cytobrush)
• Urethral Swab (Sterile Container without Gel – 2 swab samples)
Patient requirement– No fasting required
– Ideal sampling is 2 weeks (10 – 18 days) after the first day LMP
– Avoid sampling during menstrual period
– Avoid intercourse, douching, or using any vaginal medicines or spermicidal foams, creams or jellies 2 days before sampling
Storage & transportationPlease keep at room temperature
Turnaround Time (TAT)5 working days

FAQ

Why is HPV testing important?

The test detects and identifies the HPV types infecting the cervix.  It allows earlier detection, even before the cell changes occurred. Early detection of high-risk HPV helps prevent cervical cancer through timely monitoring and treatment.

Having a high risk HPV type does NOT mean you have or will get cervical cancer. If your HPV test is positive for high-risk HPV you will need further investigation to check for any cellular changes in the cervix. If serious cellular changes are found they can be treated before it leads to cancer.

All women age 25 – 65 years old, which have had sexual activities should go for the test. Vaccinated women are encouraged to continue with routine screening.